Alexis Bledel, America Ferrera, Amber Tamblyn, and Blake Lively in The Sisterhood of the Traveling Pants 2 Courtesy of Warner Bros.

Read Premiere's review of Sisterhood 2

Alexis Bledel, Blake Lively, America Ferrera, and Amber Tamblyn have grown up since The Sisterhood of the Traveling Pants in 2005, and so have their careers. When we first laid eyes on America Ferrera, she was playing a blossoming Mexican-American teenager in Real Women Have Curves. Since then Ferrera's career has skyrocketed thanks to her endearing character on the primetime Emmy-winning show Ugly Betty. Similarly, Blake Lively's role in The Sisterhood of the Traveling Pants led to her figurehead status in Gossip Girl, a contemporary Dynasty chronicling the liaisons of an elite Upper East Side prep school. Audiences also fell in love with Alexis Bledel in the seven year run of Gilmore Girls, while Amber Tamblyn, who previously starred in the TV show Joan of Arcadia, has been testing her acting chops with roles in dramas like Stephanie Daley.

Together, the four are witty, articulate, and clever — and not just for the teen market. In the Sisterhood sequel, they confront universal coming-of-age problems like fears of growing apart, pregnancy scares, first loves, and new cities. Premiere caught up with the cast to talk about how they've changed since their first movie together, keeping in touch, avoiding the gossip pages, and upcoming projects.

America, when you read through the script and saw, "Wow, I get the [part in the] play and I get the guy," were you just psyched by your part?... Were you just like, "This rocks"? How did you feel about developing Carmen in that direction?
America Ferrera: Well, one of the things that I thought would be interesting for this character in the next movie is that she's a very different character than what we saw in the first film. I think in the first movie she was a lot more extroverted and kind of the glue that held the sisterhood together, and she was trying very hard to make all those things mean something. [In the sequel] you catch up with her at a point where she's kind of sick of being the glue, and she's just like, "Well, if no one else is going to try, then why should I?" And I liked that she was struggling through something and was forced to do it on her own, and that her friends couldn't help her through what she was going through. I think that the issues she was going through in the first movie are just carried into this and have worsened her issues of abandonment. I mean, in the first movie her father is moving on and starting a new family, and in this movie her mother is moving on and starting a new family, and her friends are moving on, so she's got to deal with feeling alone again. And she has to do it on her own, which I think is her journey in growing up.

What was it like working in Greece, and which was the scarier moment for you: riding a donkey or taking the plunge?
America Ferrera: Or riding mopeds.

Amber Tamblyn: Probably neither of those. [laughter among cast]

Amber Tamblyn: We got in a tiny little moped accident the very first day of shooting, and actually Blake hurt her knee really bad, and America fell off her bike and spun around, and it was very dramatic and great for our first day of shooting.

Blake Lively: It really set the tone.

Alexis Bledel: That was definitely the scariest.

Amber Tamblyn: It was good because I got to make fun of them on crutches.

Blake Lively: She would take our crutches too. She would, like, go in our room and steal them. But that was the scariest.

Alexis Bledel: The donkeys were fun. The donkeys were whatever. They're easy. You just sit on them.